The Southampton midfielder was a priority for Spurs last summer but Saints held firm and relations between the clubs turned sour as a result.
Arsenal are now said to be interested in Wanyama ahead of the January transfer window but Saints boss Koeman warned: “Don't spend time trying to buy a player from Southampton because it's impossible.
“They can prepare whatever they like to prepare. They talk about players from Southampton because we have some good players and there is always interest in players.
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“And the ambition of players is about playing Champions League. We know what we like to do and how we like to do our business. That means in January nobody will leave Southampton.”
Spurs were prepared offer Andros Townsend or Erik Lamela plus cash to land Wanyama last summer but Southampton were unmoved and it appears their stance will remain the same next month.
