Andre Villas-Boas has recalled Roberto Soldado after he dropped to the bench for Tottenham's last Premier League match against West Ham.
Jermain Defoe is sacrificed for the Spaniard and Vlad Chiriches makes his Premier League debut.
Lewis Holtby comes in for Christian Eriksen while Paul Lambert has named an unchanged Villa side who will be buoyed by the return of Christian Benteke; the Belgium international is among the substitutes.
Aston Villa: Guzan, Bacuna, Vlaar, Baker, Luna, El Ahmadi, Westwood, Delph, Weimann, Kozak, Agbonlahor. Subs: Steer, Helenius, Sylla, Benteke, Bowery, Tonev, Lowton.
Tottenham: Lloris, Walker, Dawson, Chiriches, Vertonghen, Paulinho, Sandro, Townsend, Holtby, Sigurdsson, Soldado. Subs: Lennon, Defoe, Dembele, Friedel, Naughton, Eriksen, Lamela.
