The woman, in her 30s, suffered serious injuries in the collison on Great Dover Street at 8.22am on Thursday.
Horrific footage on social media shows the victim covered in a foil blanket as she receives first aid at the scene from paramedics.
Nigel Carroll, who lives close to the scene of the collision, said he heard “ a bang” and looked out at the scene.
He told the Standard: “It’s quite a busy road. Cars do go quite fast, no bike or bus lane along this part of the route, quite tight for two lanes.”
A Met spokesman said: “The cyclist, a woman in her 30s, has been taken to hospital. Her injuries were assessed as non-life threatening.
“Road closures have been put in place.
“Enquiries are ongoing and no arrests have been made.”
A London Ambulance Service spokesperson said: “We were called at 8.22am today to reports of a road traffic collision involving a cyclist and a truck on Great Dover Street, SE1.
“We sent an ambulance crew, a medic in a car, and an incident response officer. We also dispatched by road London’s Air Ambulance.
“A woman was treated at the scene and taken to a hospital as a priority.”
